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Anna Tempczyk-Russell

Scientific Advisor @ Eli Lilly and Company

Research Advisor at Eli Lilly

Greater San Diego Area

Ranked #1,053 out of 21,060 for Scientific Advisor in United States

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Anna Tempczyk-Russell's Email Addresses & Phone Numbers

Anna Tempczyk-Russell's Work Experience

Eli Lilly and Company

Scientific Advisor

February 2014 to Present

Greater San Diego Area

Pfzer

Principal scientist

February 2011 to May 2013

Pfizer

Principal Scientist

February 2011 to May 2013

Greater San Diego Area

Anna Tempczyk-Russell's Education

Columbia University in the City of New York

Ph.D. Solvation model stochastic dynamics

1988 to 1990

Columbia University in the City of New York

Post Doctoral Generalized Born Model

1988 to 1989

University of Gdansk

PhD Quantum Physics

1974 to 1988

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Anna Tempczyk-Russell's Estimated Salary Range

About Anna Tempczyk-Russell's Current Company

Eli Lilly and Company

Frequently Asked Questions about Anna Tempczyk-Russell

What company does Anna Tempczyk-Russell work for?

Anna Tempczyk-Russell works for Eli Lilly and Company


What is Anna Tempczyk-Russell's role at Eli Lilly and Company?

Anna Tempczyk-Russell is Scientific Advisor


What is Anna Tempczyk-Russell's personal email address?

Anna Tempczyk-Russell's personal email address is t****[email protected]


What is Anna Tempczyk-Russell's business email address?

Anna Tempczyk-Russell's business email addresses are not available


What is Anna Tempczyk-Russell's Phone Number?

Anna Tempczyk-Russell's phone (**) *** *** 214


What industry does Anna Tempczyk-Russell work in?

Anna Tempczyk-Russell works in the Research industry.


About Anna Tempczyk-Russell

📖 Summary

Experienced industry scientist with expertise in computational biology, chemistry, molecular modeling, cheminformatics, proteomics, in silico protein engineering, structure based drug design, computational chemistry, quantum chemistry, data base administration, intellectual property, and project management. Therapeutic fields where expertise was applied: Immunology including but not limited to receptor-ligand interactions, discovery of inhibitors for protein phosphatases, protein kinases, cell surface receptors, MHC peptide epitop, gene expression analysis Anti-cancer - VEGRr inhibitor Axitinb (1 billion dollar Pfizer drug) ACD and PDC site specific conjugation. ADC and PDC site specific directional conjugation (patent) GPCR homology modeling and discovery of GPCR modulators. Annotation and modeling of antibodies, CDR optimization, antibody humanization, discovery of protein based antigens Metabolic Diseases - GPCR, GPR and FGF receptors-ligands Crops protecting insecticides (Vestaron story) Definition of novel methodologies Generalized Born Model, QM/MM, automatization of repeatable modeling processes. Proven record of more then 70 publications and patents( List can be e-mailed upon request)Scientific Advisor @ From February 2014 to Present (1 year 11 months) Greater San Diego AreaPrincipal scientist @ Anna Tempczyk-Russell, Ph.D: Anna earned her Ph.D. in the field of quantum physics championing formulation of solvation models for molecular simulation. Anna continued her work on solvation models at Columbia University, which resulted in the definition of the Generalized Born solvation model, the gold standard for implicit solvent simulations. Over the last 20 years Anna has gained extensive scientific knowledge working for large pharmaceutical and small biotechnology companies corroborated by many publications and patents. Anna’s expertise comprises but is not limited to, of proteomics, structure based design, protein kinases, antibodies modeling, GPCRs, proteases, nuclear hormone receptors and others. Anna has established a long record of successful and unique solutions to scientific problems. From February 2011 to May 2013 (2 years 4 months) Principal Scientist @ Most recently, I was employed by Pfizer-CovX Company where my primary responsibility was to deliver solutions and support to CovX research project in the field of protein engineering, bio-conjugation, bioinformatics, and peptide SAR. My interest in computational methods began with my doctorate thesis in quantum physics and continued with post doctoral work under Prof. Clark W. Still at Columbia University, where I developed continues solvation model, which today it is known as the GENERALIZED BORN MODEL. The citation number of this original publication (Semi analytical treatment of solvation for molecular mechanics and dynamics W. Clark Still, Anna Tempczyk, Ronald C. Hawley, Thomas Hendrickson; J. Am. Chem. Soc.; 1990; 112(16); 6127-6129 has exceeded 1800 and the number is growing. From February 2011 to May 2013 (2 years 4 months) Greater San Diego AreaSenior Principal Investigator @ CHUGAI BIOPHARMACEUTICALS, INC., San Diego, CA Project leader of the discovery vitamin D non-secosteroidal modulators. Data base mining/docking, computational molecular biology, combinatorial virtual libraries development. Application of QSAR method to predict ADME parameters for drug candidates. Discovery of non-secosteroidal nuclear hormone receptor agonist and antagonists. Project managment web pages development, design and administration. Supervise Oracle data base registry. From September 2005 to May 2012 (6 years 9 months) Senior principal @ Senior Principal Scientist, project leader for nonsechosteroidal vitamin D mimetics From 2001 to 2005 (4 years) senior scientist @ Structural Biology, Bioinformstics, database From 1993 to 2001 (8 years) senior scientist @ Scientist, Adhesion molecules, their interaction and interaction modifications From 1991 to 1992 (1 year) Ph.D., Solvation model, stochastic dynamics @ Columbia University in the City of New York From 1988 to 1990 Post Doctoral, Generalized Born Model @ Columbia University in the City of New York From 1988 to 1989 PhD, Quantum Physics @ University of Gdansk From 1974 to 1988 PhD, Quantum Physics @ University of Gdansk From 1974 to 1988 Anna Tempczyk-Russell is skilled in: Cheminformatics, Computational Chemistry, Drug Discovery, Drug Design, Molecular Modeling, Bioinformatics, Lifesciences, Biotechnology, Computational Biology, Biomarker Discovery, Lead Change, Chemistry, Molecular Biology, Biochemistry, Medicinal Chemistry


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Anna Tempczyk-Russell's Personality Type

Extraversion (E), Intuition (N), Thinking (T), Judging (J)

Average Tenure

3 year(s), 9 month(s)

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