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Karen Wetterhahn's Email & Phone Number

American professor


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About Karen Wetterhahn

📖 Summary

Karen Wetterhahn was an American professor and chemist who made significant contributions to the field of toxicology. Born in 1948 in Plattsburgh, New York, Wetterhahn became recognized for her pioneering work in heavy metal poisoning. She is best known for her tragic death resulting from exposure to a few drops of dimethylmercury, a potent neurotoxin.

Wetterhahn's academic career was marked by numerous achievements and accolades. She received her bachelor's degree in chemistry from St. Lawrence University, followed by a Ph.D. in inorganic chemistry from Columbia University in 1976. She then joined the faculty at Dartmouth College, where she rose through the ranks to become the Chair of the Chemistry Department. Her research focused on the mechanisms of heavy metal toxicity, particularly the effects of mercury on the central nervous system.

Wetterhahn's work was groundbreaking and shed light on the insidious effects of heavy metal exposure on human health. She was particularly interested in the biochemistry of mercury and its compounds, aiming to understand how they interacted with biological systems at the molecular level. Her research had important implications for public health, as it highlighted the need for stricter regulations on mercury exposure in industrial and laboratory settings.

In August 1996, Wetterhahn's life took a tragic turn when a few drops of dimethylmercury penetrated her protective gloves during an experiment. Despite following safety protocols, the highly volatile compound was able to seep through the butyl rubber material, ultimately leading to her exposure. Initially, Wetterhahn showed no signs of illness, but within months she began experiencing symptoms of mercury poisoning, including headaches, slurred speech, and loss of coordination.

Despite aggressive treatment, Wetterhahn's condition rapidly deteriorated, and she passed away in June 1997, just over a year after the incident. Her death shocked the scientific community and prompted a reevaluation of safety protocols in laboratories working with toxic substances. Wetterhahn's tragic passing served as a stark reminder of the potent dangers of working with certain chemicals, even for experienced and cautious researchers.

Wetterhahn's legacy lives on through her enduring contributions to the field of toxicology. In addition to her scientific accomplishments, she is remembered as a dedicated mentor and advocate for women in STEM fields. Her pioneering research on heavy metal poisoning has had a lasting impact on the understanding of toxic substances and continues to inform safety standards in research laboratories and industrial settings.

Overall, Karen Wetterhahn's life and career serve as a testament to the pursuit of scientific knowledge and the importance of prioritizing safety in research environments. Her untimely death was a tragic reminder of the risks inherent in experimental work, but her enduring contributions to the field of toxicology continue to inspire future generations of scientists. Karen Wetterhahn's legacy serves as a reminder of the profound impact that one individual can have on the scientific community and the world at large.


Frequently Asked Questions about Karen Wetterhahn

Why is Karen Wetterhahn famous?

An expert in the mechanisms of metal toxicity, Professor Wetterhahn was best known for her research on chromium, but also conducted significant research on mercury. She became ill and died in 1997, at the age of 48, as a result of a tragic laboratory accident involving a highly toxic mercury compound.


Why is dimethylmercury so toxic?

Why is dimethylmercury toxic? It is one of the most potent neurotoxins known. It readily crosses the blood-brain barrier, probably due to its formation of a methylmercury-cysteine complex. It causes ataxia (lack of coordination), sensory disturbance and changes in mental state.


What is the most toxic organic mercury?

Dimethylmercury is an extremely toxic organomercury compound with the formula (CH3)2Hg. A volatile, flammable, dense and colorless liquid, dimethylmercury is one of the strongest known neurotoxins. Less than 0.1 mL is capable of inducing severe mercury poisoning resulting in death.


Is elemental mercury more toxic than dimethylmercury?

Although it is less toxic than methylmercury, elemental mercury may be found in higher concentrations in environments such as gold mine sites, where it has been used to extract gold. If elemental mercury is ingested, it is absorbed relatively slowly and may pass through the digestive system without causing damage.


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