I am passionate about helping people in different research fields with my specialty in analytical chemistry understand nature and science, thus contributing to the improvement of people's life and health.
My technical skills in biological sample preparation, experimental design, and 1D/2D-LC-MS method development provide the foundation to my willingness to help other scientists. As an applications scientist, I have developed methods with HPLC or UPLC from Waters, Agilent, Dionex, and Michrom on regular or nano-scale coupled to either ESI ion trap or high resolution ESI-Q-TOF MS to analyze samples ranging from intact proteins to peptides and small molecules. As a research assistant, I have worked on diverse collaborated projects on peptide identification and quantitation in different biological systems such as mammalian cell lines, drosophila heads, and rat/mouse tissues with either capillary or nano-scale HPLC coupled to either ESI ion trap, ESI-Q-TOF, or MALDI-TOF/TOF MS.
At the same time, I polished my communication skills by working in a team environment, conducing customer support, and presenting my research in conferences and symposia. My verbal and written skills allowed me to clearly demonstrate the instruments, present the results, train customers in industry and academia, and answer their questions. I greatly enjoyed sharing my experience, helping others, and discussing with people from different backgrounds.
Scientist I @ From 2012 to Present (3 years) Application Scientist @ ♦ Developed LC-MS and LC-MS/MS methods (Waters UPLC, Agilent HPLC, Dionex RSLC/RSLCnano, or Michrom nanoLC coupled to Bruker ESI ion trap MS or high resolution ESI-Q-TOF MS)
♦ Run customers’ samples (intact antibodies, proteins and protein complexes, top-down and bottom-up proteomics, PTM analysis, impurity analysis, synthetic small molecules, and natural products, etc.)
♦ Demonstrated instruments and presented results to customers in industry and academia
♦ Trained customers on how to use the instruments and softwares
♦ Conducted customer support in person, by phone, email, or web conferencing From 2010 to 2011 (1 year) Reseach Assistant @ ♦ Studied peptidomes and secretomes of glial cells with multiple LC-MS techniques (e.g., CapLC-ESI-IT MS, CapLC-MALDI-TOF/TOF MS, etc.) and bioinformatics tools.
♦ Developed and employed LC-MS based methods to identify and quantify (labeling and label-free) partially and fully processed amidated peptides to investigate peptide amidation in mouse pituitary.
♦ Characterized and quantified ectopic MII peptide in Drosophila heads with CapLC-ESI-IT MS/MS and CapLC-MALDI-TOF/TOF MS/MS to study the function of a transcriptional factor.
♦ Investigated tandem MS of 5-mer peptides with NanoLC coupled to ESI-Q-TOF MS. From 2005 to 2010 (5 years) Urbana-Champaign, Illinois AreaTeaching Assistant @ ♦ Supervised a diverse student population at beginner level to conduct chemistry experiments.
♦ Monitored and assisted individuals’ progress by prompting and answering questions.
♦ Demonstrated principles and procedures in chemistry labs.
♦ Impartially evaluated student progress and provided timely feedback. From 2005 to 2007 (2 years) Urbana-Champaign, Illinois Area
Ph.D., Analytical Chemistry @ University of Illinois at Urbana-Champaign From 2005 to 2010 B.S., Chemistry @ University of Science and Technology of China From 2001 to 2005 Ping Yin is skilled in: Mass Spectrometry, LC-MS, Analytical Chemistry, Proteomics, HPLC, Chromatography, Life Sciences, Biological Sample Preparation, Cell Culture, Immunocytochemistry, Bioinformatics, Neurochemistry, Chemistry, Lifesciences, MALDI-TOF, Peptides, Laboratory, Cell, Protein Chemistry
Websites:
http://www.scs.uiuc.edu/sweedler,
http://www.vrtx.com