Director, GMP for Immunotherapy, Research Assistant Professor @ Children's National Medical Center
Post doctoral fellow @ Baylor College of Medicine
Graduate Student @ Baylor College of Medicine
Bachelor of Arts, Biology, Chemistry @
I am the director of a Class 10,000 Good Manufacturing Practices (GMP) facility where we manufacture novel cell therapies for patients enrolled on our clinical trials. Trained as an Immunologist, I have an extensive background and interest in cellular therapy. For the past 8 years I have investigated and helped to translate the following into more than
I am the director of a Class 10,000 Good Manufacturing Practices (GMP) facility where we manufacture novel cell therapies for patients enrolled on our clinical trials. Trained as an Immunologist, I have an extensive background and interest in cellular therapy. For the past 8 years I have investigated and helped to translate the following into more than 10 clinical trials:
*Virus-specific T cells for the prophylaxis and treatment of viral infections after transplant.
*Tumor-specific T cells using both endogenous receptors (targeting Glioblastoma Multiforme) as well as chimeric antigen receptors (CARs, targeting CD19-positive malignancies).
*A GMP-compliant method of manufacturing mesenchymal stromal cells (MSCs) using the Quantum cell expansion system for patients after stroke, graft-versus-host disease, and Inflammatory Bowel Disease.
I was previously supported by a nationally competitive American Cancer Society postdoctoral fellowship and was awarded the Excellence in Research award by the American Society of Gene and Cell Therapy in 2012 and the Young Investigator award by the International Society of Cell Therapy (ISCT) in 2013. I have previously served on the trainee council of the American Society of Hematology, was a trainee member of the Production Assistance for Cellular Therapy Steering Committee and also the Education Committee, and was selected for the international American Society of Hematology/EHA Translational Research Training Program.
I am currently a certified Foundation for the Accreditation of Cellular Therapy inspector, on the editorial boards of the journals Molecular Therapy: Methods and Clinical Development, and Cytotherapy, and serve on ISCT’s Immunotherapy Committee. Energetic, pragmatic, motivated, and an expert in cell therapy–particularly in the GMP setting—I am strongly suited to lead the next phase of cell therapy trials.
Director, GMP for Immunotherapy, Research Assistant Professor @ From June 2013 to Present (2 years 5 months) Washington D.C. Metro AreaPost doctoral fellow @ I currently work on bringing translational research into the clinic. Two of the projects that I work on in the Good Manufacturing Practice (GMP) facility include:
- Generating virus-specific T cells from umbilical cord blood to treat viral infections after stem cell transplantation
- Expanding allogeneic mesenchymal stromal cells (MSCs) to help offset trauma in stroke patients. From March 2011 to July 2013 (2 years 5 months) Houston, Texas AreaGraduate Student @ The overarching goal of my thesis was to protect patients from viral infections after stem cell transplantation. Specifically, I worked on generating virus-specific T cells from different donor sources (CMV-seronegative and CMV-seropositive donors as well as umbilical cord blood) for adoptive immunotherapy. This translational work has since been translated to the clinic. From August 2006 to March 2011 (4 years 8 months) Houston, Texas Area
Ph.D, Immunology @ Baylor College of Medicine From 2006 to 2011 Bachelor of Arts, Biology, Chemistry @ Hartwick College From 2002 to 2006 NYS Regents @ Irondequoit High School From 1999 to 2002 Patrick Ph.D. is skilled in: Flow Cytometry, Tissue Culture, Molecular Cloning, GMP, PCR, Mentoring, ELISPOT, ELISA, Cell Based Assays, Cell Signaling, Cell Therapy, Immunoassays, Western Blotting, Immunology, Cell Culture, Cell, Translational Research, Immunofluorescence, Cancer Research, Fluorescence Microscopy, Stem Cells, FACS, In Vitro, Virology, Gene Therapy, Scientific Writing, Animal Models, Immunohistochemistry, Transfection, Clinical Trials, Translational Medicine, Clinical Research