Children's Oncology Group

The Children's Oncology Group (COG) is a National Cancer Institute (NCI) supported clinical trials cooperative group, and the world’s largest organization devoted exclusively to childhood and adolescent cancer research. Clinical research is conducted at more than 200 member institutions, which are leading children’s hospitals, universities, and cancer centers throughout the United States, Canada, Europe, Australia, and New Zealand. COG’s over 9,000 multi-disciplinary cancer researchers, affiliated with the network of member institutions, provide access to state-of-the-art therapies and the collective expertise of world-renowned pediatric specialists to children with cancer, regardless of where they live. Today, more than 90% of 14,000 children and adolescents diagnosed with cancer each year in the US are cared for at Children’s Oncology Group member institutions. COG is primarily supported through cooperative research grants from the NCI. COG also receives funding through other federal and non-federal grants, industry contracts and philanthropic partnerships. With offices in Philadelphia, PA (Children's Hospital of Philadelphia) Monrovia, California (Public Health Institute) and Gainesville, Florida (University of Florida), COG’s overall annual operating budget is approximately $60M. Toward its mission of improving treatment by increasing cure rates and reducing side effects, COG currently conducts nearly 100 Phase I, II, and III active clinical trials and non-therapeutic biology studies, which enroll approximately 9,000 patients annually, with more than 25,000 patients in active follow up. COG’s goal is to cure all children and adolescents with cancer, reduce the short and long-term complications of cancer treatments, and determine the causes and find ways to prevent childhood cancer.