Center for Biostatistics in AIDS Research (CBAR)

The Center for Biostatistics in AIDS Research (CBAR) is located within the Department of Biostatistics at the Harvard T.H. Chan School of Public Health. CBAR's mission is to foster statistical science in clinical trials and other research studies in infectious diseases particularly HIV. CBAR pursues this mission by promoting innovative strategies for the design, data monitoring, analyses, and reporting of research studies, and by providing education and training relevant to statistical aspects of infectious disease research. As one of the largest staff Centers at the School, CBAR is comprised of >100 doctoral- and master’s-level biostatisticians, epidemiologists, and associated professional staff. These team members are at the forefront of statistical research related to the development of methods for the design and analysis of HIV clinical trials and observational studies, in the areas of HIV and infectious diseases. Our current research focuses on methods for patient-focused outcome measures that integrate efficacy and safety outcomes, for competing risks data, for personalizing treatment, and for comparison of technologies (e.g., point of care versus gold standard technologies). We also have a particular focus on the development and application of sophisticated epidemiological models for evaluating treatment benefits accounting for confounding by indication, such as the use of marginal structural models, mediation analysis, and other causal inference approaches. Our current training activities focus on programs for supporting the development of biostatistical expertise at institutions in Africa, South America, and South-East Asia. To learn more about the research projects please visit our page on the Harvard T. H. Chan School of Public Health website at: https://www.hsph.harvard.edu/cbar/