NovAliX

NovAliX provides small molecule DRUG DISCOVERY services; serving pharmaceutical companies via a unique combination of screening, medicinal chemistry & structural biology. Clients from all over the world, in key industrial sectors, rely upon the laboratories of NovAliX to deliver the innovations that future business growth depends upon through the successful completion of challenging projects. It is the personal support of the individual professionals that builds secure corporate relationships. The expertise of NovAliX ensures that our clients meet their targeted objectives. Chemical microarray SCREENING: 1) 116,000 compound library - unique & diverse, includes 25,000 fragments 2) Sensitive SPR detection well suited for fragment based drug discovery 3) Hits - validated by MS, NMR or biochemical activity. Synthetic organic & medicinal CHEMISTRY: 1) Hit to lead & lead optimization 2) Focused libraries for drug discovery 3) Process research -new practical routes 4) Custom synthesis of chemicals & reference materials 5) Cost competitive FFS/FTEs BIOPHYSICAL toolbox: 1) Crystallographic grade protein 2) Target-ligand crystal structures by XRD – large gallery 3) Native MS screening up to 2000 compounds per day 4) Binding parameters measured by SPR (Biacore), ITC, NMR 5) Cryo electron microscopy Medicinal chemists: guide optimisation from hit to clinic. CONTACT [email protected]