Cascade Chemistry

Cascade Chemistry, is a Contract Research and Manufacturing Organization specializing in solving challenging synthetic problems for the pharmaceutical and chemical industries, and helping our clients move new APIs to clinical trials. We have extensive experience in synthetic route optimization, process development, scale up, and providing chemical samples of process intermediates, process impurities, degradants, and reference standards. Our expertise includes alkaloids, heterocycles, steroids, terpenes, prostaglandins, phenylacetylenes, and chiral syntheses. Our chemists have a variety of backgrounds and assist in all areas of synthetic development from Med Chem through multi kilogram scale manufacturing. Our facilities include R&D labs, analytical labs, and kilo labs with walk in hoods and 50-100 liter reactors. Our cGMP facility matches the equipment in our kilo lab for 5 kg batch size Phase 1-2. Cascade Chemistry, formerly Organic Consultants, Inc was founded in 1980 by Lloyd Dolby, was acquired in 2021 by Aceto and is based in Eugene, OR.