Overview:We welcome clinical, biomedical, social and health services research. The Annals publishes original research, methodology, and theory, as well as essays from reflective clinicians, patients, families, communities, and policymakers. We publish selected systematic reviews that build on current knowledge to advance new theory, methods, or research directions. The Annals seeks manuscripts that use and develop rigorous quantitative and/or qualitative methods, and manuscripts with application to practice, theory development, and policy. We encourage practice-based research and research that bridges disciplinary boundaries.