- Invented novel cellular and protein assays, and co-founded Sandstone Diagnostics to commercialize these assays
- Leading development and validation of Sandstone's products
- Successfully engaged in diverse projects in medical product development, applied assay technology research, and basic immunology research
- Filed 10 domestic and international patent applications
Specialties: Agile project management, Product prototyping, Microfluidic part design, Cellular assays, Immunoassay development
Chief Technology Officer @ Primary inventor of Sandstone Diagnostics' technology
Head of assay development, prototyping, manufacturing, and product validation
Led implementation of Agile project management From July 2012 to Present (3 years 6 months) Postdoctoral Appointee @ Invented and developed SpinDx assay technology
Built a functional portable prototype assay instrument
Led development and manufacturing of injection molded disposables
Filed 8 patent applications From February 2010 to July 2012 (2 years 6 months) Post-Doc @ Developed siRNA transfection in primary neutrophils and published results in Bio-Rad Laboratories (Hercules, CA) quarterly publication
Tested therapeutic antibody on human T-cells under shear flow in conjunction with Protein Design Labs (Fremont, CA)
Published research on store operated calcium signaling in neutrophils attaching to adhesion molecules under flow
Created an internal information management website as acting lab manager (https://sites.google.com/site/simonlabwiki/) From June 2007 to February 2010 (2 years 9 months) Graduate Student Researcher/Lab Manager @ Developed novel microfluidic assay that mimics inflamed human blood vessels
Conducted research on the activation of integrins and leukocyte recruitment
Produced training program for implementation of microfluidic assays at University of Calgary
Mentored, trained, and managed 9 undergraduates co-authoring with 5 From January 2004 to June 2007 (3 years 6 months) Graduate fellow @ -Published disease and leukocyte adhesion research on SNX20 deficient mice in conjunction with Wyeth Pharmaceuticals (Philadelphia, PA)
-Applied qtPCR to DNA isolates from mice infected with disease bacteria Anaplasma phagocytophilum, extracted pathogen from mouse spleen, and developed in vitro model of disease trafficking From May 2005 to May 2007 (2 years 1 month)
Doctor of Philosophy (Ph.D.), Bioengineering and Biomedical Engineering @ University of California, Davis From 2003 to 2007 MEng, Bioengineering @ University of California, San Diego From 2001 to 2002 B.S., Bioengineering @ University of California, Berkeley From 1997 to 2001 Ulrich Schaff is skilled in: Troubleshooting, Optical Fiber, Fluorescence Microscopy, Microfluidics, Biomedical Engineering, Fluorescence, Microscopy, Cell Culture, Flow Cytometry, Assay Development, ELISA, Spectroscopy, Confocal Microscopy
Websites:
https://sites.google.com/site/simonlabwiki/,
http://www.sandia.gov