PhD in Computational Biology and Biochemistry, Northwestern Medical School, with extensive training and strong experience in unsupervised (clustering methods), and supervised machine learning, predictive modeling, statistical inference, network analysis, and experiment design. Strong background in programming in Python, C/C++, PHP. Highly experienced in collaborating with specialists in diverse fields including computer science, statistics, chemistry, biology, social science and medicine. Derives actionable insights from data. Interested in fraud detection, health-care data analytics, business analytics, and many more.

Core Data Scientist @ From October 2015 to Present (1 month) Core Data Scientist @ From July 2015 to October 2015 (4 months) Mountain View, CAData science fellow @ Developed Ovrvue (http://ovrvue.com) a web application to detect and filter explicit web content using a combination of text classification and computer vision. Combined Adaptive Boosting using Decision Tree stubs and Multinomial Naïve Bayes Classification to identify inappropriate visual and text content (respectively). Implemented Python daemons in the backend reducing server burden and enhancing application availability. From January 2015 to July 2015 (7 months) Palo Alto, CAPh D, Driskill Graduate Life-sciences Program @ Design and implementation of chemical synthesis, cell culture and animal drug treatment experiments. Micro-array analysis of gene expression profiles in cultured lymphoma cells. Clustering outlier analysis to identify anomalous gene expression profiles. RNA-RNA co-folding secondary structure prediction in silico to assess potential ribozyme-like activity. Formulation of gold nanoparticle core based biomimetic high density lipoprotein nanoparticles as carriers of RNA interference (RNAi) molecules for regulation of gene expression. In vitro assessment of reduced expression and loss of function of RNAi target VEGFR2 in endothelial cells using Western blotting, RT-qPCR, tritiated thymidine incorporation (for cellular proliferation), annexin V/PI flow-cytometric assay (for cellular apoptosis), scratch wound healing assay (for cellular chemotaxis), and matrigel tubulogenesis assay (for endothelial cell morphogenesis). In vitro study of trafficking of biomimetic HDL nano-constructs synthesized with fluorophore tagged protein component and nucleic acid cargo via confocal microscopy. In vivo studies for loss of function of RNAi target VEGFR2 in murine subcutaneous tumor and Matrigel plug models using immunohistochemical staining followed by fluorescent imaging and analysis. Quantitative and qualitative assessment of gold nano-particle core uptake through inductively coupled plasma mass spectrometry (ICP MS) and transmission electron microscopy (TEM) respectively. From September 2008 to March 2015 (6 years 7 months) Greater Chicago AreaData Analyst @ Performed cross-visitation network analysis on large data-sets and identified user niches on the Chinese internet. Employed graph visualization, clustering and correlational analysis to study cultural interaction in web usage. Setup a distributed crawling infrastructure to glean hyperlink networks within the Chinese internet. From September 2014 to December 2014 (4 months) Hong KongLead Developer @ Hired as an expert programmer in research project entitled "What balkanizes the Internet: Access denied or access unwanted". Funded by the Internet Policy Observatory, Annenberg School of Communication at the University of Pennsylvania, this project analyzes chronological global web use behavior. My contributions include developing software for calculation of custom network analytic measures and applying appropriate community detection algorithms to large data-sets. From March 2014 to July 2014 (5 months) Research mentor, CURE 2012 @ Mentored an undergraduate student in his research efforts to validate microRNA targeting in a cell free system. Introduced the student to safe work practices in the lab space and devised broad outlines of experimental strategy and helped with planning and troubleshooting experiments. Experimental methods disseminated included aseptic mammalian cell culture techniques, bacterial cell culture techniques, transformation and selection of bacteria with plasmids, isolation of bacterial plasmids, transfection of plasmids and RNA into mammalian cells, detection of luciferase reporter expression, poly-acrylamide gel electrophoresis, DNA/RNA gel electrophoresis, western blotting. From June 2012 to August 2012 (3 months) Thaxton labResearch mentor, REU 2011 @ Mentored an undergraduate student in her research efforts to to assign miRNA signatures for indolent and aggressive prostate cancer. Introduced the student to safe work practices in the lab space and helped with planning and troubleshooting experiments. Experimental methods disseminated included sterile cell culture practices, RNA extraction and enrichment for miRNA and safe RNA handling and quality control practices, DNA/RNA gel electrophoresis . From June 2011 to August 2011 (3 months) Thaxton labResearch mentor, RET 2010 @ Mentored a high school teacher in her research efforts aimed at formulating nano- siRNA delivery structures. Techniques disseminated included aseptic mammalian cell culture techniques, DNA/RNA gel electrophoresis, protein gel electrophoresis and Western blotting. Helped design an interactive module, which was implemented in a high-school classroom setting, to demonstrate changes in properties of gold nano-particles in bulk which can be exploited to identify certain DNA samples. From June 2010 to August 2010 (3 months) Thaxton LabResearch mentor, CCNE REU 2010 @ Mentored an undergraduate student in his research efforts to develop gold nano-particle conjugates for delivery of antisense oligo-nucleotides to endothelial cells. Lab techniques disseminated included DNA synthesis and HPLC purification, thiol-mediated DNA-gold nano-particle surface conjugation, aseptic cell culture techniques, transient transfection, RNA/DNA gel electrophoresis, Protein gel electrophoresis and Western blotting. Mentored the student in drafting a paper on said research which was published in Nanoscape. From June 2010 to August 2010 (3 months) Thaxton LabBachelor (with Honors) and Master of Technology @ Elucidated the structural components and activity of the central enzyme responsible for the bio-remediation activity of a novel bacterial strain under study, thus paving the path for immobilization of modified enzyme constructs in synthetic materials for more efficient one-pass bio-remediation systems. Project involved isolation and characterization of a multi-component phenol hydroxylase enzyme in a novel bacterial strain of Alcaligenes faecalis. Techniques employed included substrate-specific bacterial enrichment, optimization of non-standard bacterial media requirements, bioinformatic analysis of DNA and protein sequences, PCR primer design, Single Primer PCR, random mutagenesis, protein globular domain isolation, protein cloning, bacterial transformation, enzyme kinetics, MALDI-TOF From August 2003 to May 2008 (4 years 10 months) Kharagpur Area, IndiaSummer Intern @ Worked on project entitled "Defining X-ray crystallographic conditions for HIV-1 integrase in complex with transcriptional co-activator p75". A truncated His6- tagged HIV-1 integrase construct in an inducible vector was used to transform E coli. Subsequently, after achieving adequate protein expression and optimizing purification protocol via HPLC followed by SEC, the expression was scaled up using a fermentor to yield sufficient amount of protein for subsequent activity assays. From May 2006 to August 2006 (4 months) Engelman LabSummer Intern @ Bacteria isolated from cattle refuse, meat and soil around cattle holding grounds were enriched for antibiotic resistant pathogenic bacteria and the type of antibiotic resistance genes were identified using a variety of molecular biological techniques including PCR, DNA sequencing, Southern blotting and pulse field gel electrophoresis. From May 2005 to July 2005 (3 months) Barton Lab

Doctor of Philosophy (Ph.D.), Driskill Graduate Life-sciences Program, A @ Northwestern University - The Feinberg School of Medicine From 2008 to 2015 Bachelor of Technology (B.Tech.), Master of Technology (M. Tech.), Biochemistry and Biochemical Engineering, A @ Indian Institute of Technology, Kharagpur From 2003 to 2008 Sushant Tripathy is skilled in: Machine Learning, Computer Vision, Algorithm Design, Python, PHP, JavaScript, Cassandra, HPLC, Transmission Electron..., Nanoparticles for drug..., Fluorescence Microscopy, Dynamic Light..., MySQLi, ElasticSearch, Purification, Biotechnology, PCR, Molecular Biology, Mammalian Cell Culture, Western Blotting, Nanotechnology