Ping Du's Email Addresses & Phone Numbers

📖 Summary

Sr. Director, Scientific Analytics and Informatics @ Allergan, Inc. Sr. Director, Scientific Analytics, 2014-2015Sr. Director, Research and Pharmaceutical Informatics, 2012-2014Director, Research Informatics, 2004-2011Oversaw informatics support for Research (biology and chemistry), Drug Safety Evaluation (pharmacokinetics and toxicology), Pharmaceutical Sciences (formulation, drug delivery, and clinical supplies), and Application Architecture• Interface with R&D senior management in aligning analytics and informatics goals with Research, Non-clinical Development, Pharmaceutical Sciences, and Global Safety objectives. • Manage R&D business strategic initiatives to improve operational efficiency.• Facilitate the Functional Steering Board meetings to prioritize technology project portfolios based on business drivers. • Develop and own the detailed three-year technology strategy roadmaps. Oversee computer systems support, data analytics services, and project management to execute the strategy effectively. • Responsible for developing an R&D-wide IT architecture in data warehouses, business intelligence, Web portal, integration, collaboration, document content management, enterprise search and digital signature. • Partner with Information Technology and Quality Assurance to deliver informatics projects timely, within budget, and in compliant with relevant regulations. • Lead Scientific Analytics in support of drug discovery, clinical trial site selection, high-value patients identification, and drug safety reporting for enhanced innovation. • Build and grow teams, manage technical resources, and cost center budget to achieve predefined business and technology goals. From June 2004 to June 2015 (11 years 1 month) Irvine, CADirector, Informatics @ Adaptive Therapeutics Build an informatics capability for the biotech start-up.• Establish informatics capabity for a biotechnology startup. • Collaborated with R&D scientists to develop a strategy in scientific data management, analysis, and computer systems. • Managed software development and information system projects in support of cyclic peptide discovery as anti-fungal agents. From August 2002 to September 2003 (1 year 2 months) San Diego, CADirector, Cheminformatics @ Lexicon Pharmaceuticals Director, Cheminformatics, 2000-2002Group Leader, Cheminformatics, 1998-2000Lead the cheminformatics group in supporting drug discovery programs, including medicinal chemistry, combinatorial chemistry, biological assay development, and lab automation.• Built the company’s high-throughput chemistry platform and to deliver screening library chemical structure and characterization information to clients. • Partnered with scientists in planning projects in chemical registration, systems integration, data analysis, and laboratory automation. • Created a novel method to represent stereoisomers in the chemical data cartridge to ensure that unique structures were accurately identified and registered. • Built a normalized data model, created an Oracle database, and developed software in C# for a homegrown lab information management system. • Managed computer programming resources to design and develop cheminformatics systems for combinatorial chemistry, analytical testing, and biological screening. From 1998 to 2002 (4 years) East Windsor, NJSr. Scientist @ Synaptic Pharmaceutical Senior Scientist, Computational Chemistry, 1996-1998Scientist, Computational Chemistry, 1994-1996Perform computational chemistry and computational structure biology research for drug lead discovery and optimization• Built predictive computational models in support of drug lead discovery and optimization. • Participated in a multidisciplinary team to improve compound leads as neuropeptide Y antagonists from micromolar to nanomolar potency. • Partnered with chemists and biologists to elucidate the structure and function of G-protein coupled receptors, resulting in a novel derivative of the drug lead while retaining biological activity. • Collaborated with the combinatorial chemistry group in designing drug-like combinatorial libraries using 2-D and 3-D molecular descriptors. From July 1994 to August 1998 (4 years 2 months) Paramus, NJComputational Chemist @ Molecular Research Institute Conduct research on protein structures and molecular spectra using computational tools• Studied peroxidase activities using semi-empirical calculations, molecular dynamics simulations, and homology modeling methods. • Applied electronic configuration interaction methods to gain insight into the electronic structure of protein intermediate complexes. • Developed a novel method to predict rhodopsin 3-D structure de novo using sequence divergence analysis. From July 1990 to June 1994 (4 years) Palo Alto, CASr. Director @ Bristol Myers Squibb San Diego, California, United StatesDirector, IT Business Partner @ Celgene Manage informatics strategy, prioritization, project portfolio, and process improvement for the drug discovery organization. Collaborate with IT functional groups to deliver informatics capabilities. From July 2015 to November 2019 (4 years 5 months) Greater San Diego Area