Project Manager/Scientist at AstraZeneca
Gaithersburg, Maryland, United States
LabCorp Clinical Trials
February 2014 to Present
May 2010 to February 2014
Seattle Children's Hospital
2009 to May 2010
Associate Scientist II
June 2005 to December 2008
Senior Research Associate
September 2001 to June 2005
February 2000 to October 2001
• Lead validation of new genomics protocols and molecular assay development in a regulated setting. • Strong understanding of regulatory status of genomics and genetics technologies as they pertain to molecular diagnostics •Serves as PI and Project Manager for several GLP/CLIA studies • Lead validation of new genomics protocols and molecular assay development in a regulated setting. • Strong understanding of regulatory status of genomics and genetics technologies as they pertain to molecular diagnostics •Serves as PI and Project Manager for several GLP/CLIA studies
What company does Melissa Reyes work for?
Melissa Reyes works for LabCorp Clinical Trials
What is Melissa Reyes's role at LabCorp Clinical Trials?
Melissa Reyes is Development Scientist
What industry does Melissa Reyes work in?
Melissa Reyes works in the Biotechnology industry.
Experienced biologist with extensive laboratory skills including molecular biology and specializing in immunology. Demonstrated success in project management in a biopharmaceutical setting. Highly motivated to learn state of the art methods to discover and validate novel small molecules and biologics -Enthusiastic, creative researcher with excellent critical thinking, communication and organizational skills. - Understanding of molecular signaling pathways with passionate commitments to contributing to drug development. - Works effectively both independently and in team-base environments with the ability to balance several projects by prioritizing appropriately to meet required deadlines.Development Scientist @ • Lead validation of new genomics protocols and molecular assay development in a regulated setting. • Strong understanding of regulatory status of genomics and genetics technologies as they pertain to molecular diagnostics •Serves as PI and Project Manager for several GLP/CLIA studies From February 2014 to Present (1 year 11 months) Scientist I @ • Drive the development of genomics assays (SNP genotyping, gene expression, RT-PCR, qPCR and microarray) according to ISO/GLP/CLIA standards. • Work with clients to select a suitable genomic assay for biomarker development and establish performance criteria to meet the client’s need. • Design and execute biomarker validation experiments, create validation plans and reports. • Analyze multivariate assay data using statistical tools. • Interact with Operations, QC, QA and Project Management teams to support timely protocol documentation and training From May 2010 to February 2014 (3 years 10 months) Laboratory Manager @ From 2009 to May 2010 (1 year) Associate Scientist II @ •Development of genomic assays to monitor pharmacodynamic markers for clinical and pre-clinical studies. • Conduct miRNA isolation and profiling using Applied Biosystems Arrays • Develop and optimize microarray hybridization methods. • Extract RNA from whole blood, tissues, cell lines, and other sources. • Perform processing and preparation of mRNA from T7 labeling to hybridization using the Affymetrix GeneChip MicroArrays. • Provide assistance and training to lab members in highly specialized techniques. • Evaluate and develop new or improved strategies for expression based assays. • Edit and assist with preparing clinical trial protocols for Pharmacogenomics/Biomarker Group • Perform Allellic Discrimination/SNP Genotyping Assays. • Present project updates and experimental data at interdepartmental meetings From June 2005 to December 2008 (3 years 7 months) Senior Research Associate @ • Implemented Molecular Pathology platforms to assist in target validation and screening of oncology small molecule and antibody therapeutic candidates. • Analyze gene expression using immunohistochemistry, microarrays, and real time PCR. • Manage all RNA/cDNA databases for inventory, experiment, and quality control. • Compose weekly production reports including: turnaround time, success rates, total production and appropriate troubleshooting actions for senior management. • Develop and revise cGLP Standard Operating Protocols for departmental usage. • Contribute to the RNA/cDNA Inventory Management Database development and data migration; Key participant in the implementation and integration of database into group production. From September 2001 to June 2005 (3 years 10 months) Research Associate @ • Develop and perform PCR/RFLP assays. Run agarose and acrylamide gel electrophoresis and genotype thousands of samples. • Perform DNA/RNA extractions from various sources such as whole blood, buccal washes and nuclear pellets. • Optimize assays on the TaqMan ABI 7700. Perform large-scale high throughput experiments for mutation, viral detection, and allelic discrimination. • Develop and maintain custom databases for all data. Develop reports for presentations and customer information. • Retroviral vector design and development, generation and evaluation of infectious retroviral vectors, adenoviral vector development and retrovirus receptor cloning. • Train three other laboratory technicians and supervise their work. From February 2000 to October 2001 (1 year 9 months) M.S., Biotechnology @ The Johns Hopkins University From 2006 to 2009 Bachelor of Science (B.S.), Biology, General @ University of Maryland College Park From 1995 to 1999 Melissa Reyes is skilled in: PCR, qPCR, RT-PCR, RNA isolation, Western Blotting, ELISA, Immunohistochemistry, DNA extraction, Molecular Biology, Cell Culture, Genomics, Cell Based Assays, Life Sciences, DNA, Immunology
Extraversion (E), Sensing (S), Thinking (T), Perceiving (P)
2 year(s), 7 month(s)
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