Fatima Mechta-Grigoriou
Head of Stress and Cancer Laboratory
Directeur de recherche chez Institut Curie - Inserm
Paris Area, France
Section title
Fatima Mechta-Grigoriou's Email Addresses & Phone Numbers
Fatima Mechta-Grigoriou's Work Experience
Institut Curie - Inserm
Head of Stress and Cancer Laboratory
2006 to Present
Paris Area, France
INSERM
Principal Investigator, Research Director (DR1 Inserm)
2006 to Present
Institut pasteur, Paris
Researcher
2000 to 2005
Ecole Normale Supérieure
Post-doctoral scientist
1996 to 1999
About Fatima Mechta-Grigoriou
📖 Summary
My laboratory, located at the "Institut Curie" in Paris (France), is devoted to the better understanding of pathophysiological consequences associated to chronic oxidative stress. The discovery of free radicals -highly unstable molecules present at low levels in our body- have greatly modified our view of certain biological processes. Free radicals are constantly produced in the body, notably by metabolism and cellular respiration, but this physiological production is controlled by “antioxidant” defense systems. However, when an imbalance arises, either because of antioxidant deficiency or overproduction of radicals, the excess of these radicals becomes toxic and is called “oxidative stress”. Now, the toxic derivatives of oxygen (or ROS, reactive oxygen species) are implicated in numerous diseases, including cancer. If we can understand the mechanisms that lead to accumulation of ROS, we will be better equipped to fight against cancer.Head of Stress and Cancer Laboratory @ From 2006 to Present (9 years) Paris Area, FrancePrincipal Investigator, Research Director (DR1 Inserm) @ From 2006 to Present (9 years) Researcher @ From 2000 to 2005 (5 years) Post-doctoral scientist @ From 1996 to 1999 (3 years) Habilitation à diriger les recherches, Biology @ Université Paris Descartes From 2005 to 2005 Doctorat, PhD, Biology @ From 1990 to 1995 Fatima Mechta-Grigoriou is skilled in: Cancer Research, Oxidative Stress, Tumor micro-environment, miRNA, Metabolism, Aging, Breast Cancer, Ovarian cancer, Angiogenesis, DNA repair, Transfert de protéines, Recherche en oncologie, Biotechnologie, Génétique, Biologie cellulaire, Biologie moléculaire
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Fatima Mechta-Grigoriou's Personality Type
Extraversion (E), Intuition (N), Feeling (F), Judging (J)
Average Tenure
6 year(s), 6 month(s)
Fatima Mechta-Grigoriou's Willingness to Change Jobs
Unlikely
Likely
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Fatima Mechta-Grigoriou's Achievements
Chevalier de l'ordre National du Mérite
Issued by - · 2013
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